Do you think that high creatinine level cannot be reduced? And it will definitely develop into uremia finally?
Actually creatinine is really more complicated than protein urine. Protein urine can be reduced by effect of steroid、immunosuppressor、anti-inflammatory drug、blood pressure tablet and etc. While here is almost no specific medicine for high creatinine level. So that people will think here is no treatment for it.
High creatinine level is usually related to uremia. Creatinine is one kind of matabolic waste which means kidneys are damaged when it accumulates in blood. The higher the creatinine level, the more damage the kidneys. If you can not discharge creatinine out of your body timely, it is easy to get uremia.
So if it is must be uremia if creatinine level increases? No.
Though high creatinine is one of feature of uremia, here are other key points to judge kidney function-GFR (glomerular filtration rate), urine protein and high blood pressure. You need make clear about these figures which is helpful for your treatment.
So over 50% of kidney damage rather than high creatinine will increase risk of uremia.
And not all high creatinine level can not be reduced. The following 2 conditions is hopeful!
1. Here is acute factor that exists in the chronic kidney disease.
In the treatment of chronic kidney disease, here is possible an acute factor which aggravate patient’s condition like cold, fever or other infection. These factors can make creatinine level increase suddenly and higher.
2. No-chronic kidney disease factors
It is common seen in summer when the weather is hot, more sweating, less water intake which makes hemoconcentration and high creatinine level. Further, suddenly strenuous exercise can lead to rhabdomyolysis. So that myohemoglobin accumulates in kidney tubules which results in acute kidney damage.
So if we can find these factors timely and correct them, patient’s condition can recover.
Honestly speaking, it is abnormal if creatinine level increase 200-300umol/L in one week. It is controllable though creatinine increase small. Please do not just wait.
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