She is a patient from Uzbekistan, diagnosed with IgA Nephropathy, and she always depends on steroids, sometimes good, sometimes bad..the condition relapsed many times. I was diagnosed with IgA nephropathy grade 4 through renal puncture surgery. The treatment effect was not good. So she visited here for Chinese medicine treatment, then IgA nephropathy grade 4 really can not be treated?
There are more than 2 million nephrons in the kidney, and about 20 are removed by renal puncture, which is one in 100,000. How can this small proportion accurately represent the whole? There may be large errors or misdiagnosis.
Pathology has its limitations, and today, no test can accurately predict the final outcome of kidney disease.
To evaluate whether the nephropathy is serious or not and how serious it is, pathology checking is just one aspect, and a comprehensive evaluation should also be combined with blood, urine, and B-ultrasound. Pathology is a reference for evaluating the condition, not a final judgment. “Kidney puncture theory” is not desirable.
How can we judge the severity of kidney disease?
It should be combined with blood tests, urine tests, B-ultrasound, pathology, age, and other related organ functions.
In some patients with pathological grade 4 IgA nephropathy, renal function is normal. Moreover, after treatment with a system of integrated traditional Chinese and western medicine, urine protein was completely relieved, and kidney function remained normal after many years. The pathology is indeed serious, but can it be said that it is not saved? Absolutely not. This is not the same as “Chronic Kidney Disease Stage 4”. Stage-4 and grade-4 may be quite different. Even with IgA nephropathy grade-5, there are a few patients whose condition have not progressed for many years.
Other nephropathy is the same situation, say membranous nephropathy stage 3-4, severe mesangial hyperplasia, lupus type 3-6, type 2 membranous hyperplasia, etc., are more serious pathologies, but there are still some patients who have remained stable for years. Some patients have severe pathology, but kidney function kept stable; some patients have mild pathology, but later develop into renal failure and uremia, such cases are innumerable.
Therefore, we look at the severity of the disease, not just the present, but also how it will develop in the future. The most important thing is to see how the medication responds and how effective the treatment is. This is the most convincing way to predict the outcome of kidney disease.
IgA nephropathy level 4 with biopsy needs to be diagnosed and treated according to the condition, the degree of damage is clarified, and the treatment is based on syndrome differentiation.